Prediction of Urinary Tract Infection in Neonates with Unexplained Indirect Hyperbilirubinemia

Background: Neonates with urinary tract infection (UTI) are susceptible to higher rates of morbidity and mortality, specifically when presented hyperbilirubinemia. Screening for UTIs in jaundiced neonates is a cost-effective strategy. The aims this study were investigate the pattern UTI (prevalence, etiology, antimicrobial agents) admitted NICU unexplained indirect hyperbilirubinemia, as well identify early predictors order reduce present long-term consequences patients.
 . Methods: A cross-sectional hospital-based that included 140 diagnosed hyperbilirubinemia first 4 weeks life. questionnaire was applied obtain demographic clinical data. number laboratory parameters assessed examination. Bacterial growth 1 × 103 colony-forming units/mL single uropathogen used existence UTI. Multivariate analysis predicting factors UTIs. Results: In group investigated, 25.7% subjects had culture-proved most frequently isolated organism Escherichia coli. Amikacin common antibiotic isolates to. multivariable logistic regression analysis, positive urine culture statistically associated an increase WBCs (OR= 6.90, p= 0.001), pyuria 5.55, small gestational age 4.07, 0.021), prolonged phototherapy duration 3.50, 0.034), presence obstetric complications 2.92, 0.001). Conclusion: substantially prevalent among importance routine screening (urine culture) part assessment highlighted study, particularly leukocytosis, pyuria, age, phototherapy, those born from mothers history complications.